Vitamin D metabolites and Vitamin D-binding protein

The laboratory offers specialized testing of various Vitamin D metabolites and Vitamin D-binding protein.    

Measurement of Vitamin D is difficult  and is explained by a combination of hydrophobicity, the avidity to binding to vitamin D-binding protein (DBP) and the presence of a large number of similar molecular forms. 

Vitamin D metabolites are measured using state of the art techniques based on liquid chromatography tandem mass spectrometry (LC-MS/MS).

Vitamin D-binding protein is measured using an ELISA assay.

The  analyses of  Vitamin D metabolites and binding protein for clinical use comprise:

  • P-25-hydroxy Vitamin D3
  • P-25-hydroxy Vitamin D2
  • P-1,25-hydroxy Vitamin D3
  • P-Vitamin D-binding protein

Bone metabolism

The following markers of bone metabolism are offered:

Markers of Bone formation:

  • P-Osteocalcin
  • P-Bone specific alkaline phosphatase
  • P-Procollagen I N-terminal propeptide (PINP)

Markers of Bone resorption:

  • P-CTX-I (crosslinked C-terminal telepeptide of type I collagen)

Further information

Please contact MD, PhD Lene Heickendorffleneheic@rm.dk, Tel +45 7845 5180.

Revised: 5 April 2017