Clostridium Difficile infection and faecal microbiota transplantation
The aims are to investigate
- associations between increasing age and frailty in a Danish population of older patients with Clostridium Difficile Infection (CDI)
- risk factors for CDI recurrence and mortality in a Danish population of patients with CDI aged 75+ years
- whether an early, multi-disciplinary geriatric tailored intervention, including geriatric assessment of the indication for faecal microbiota transplantation (FMT) and follow-up in a cooperation with the primary sector, is able to improve survival as compared to standard care in patients aged 75+ years
Contact: Tone Rubak
Collaborator: Department of Hepatology and Gastroenterology
Publication: Jørgensen SMD, Rubak TMM, Damsgaard EM, Dahlerup JF, Hvas CL. Faecal microbiota transplantation as a home therapy to frail older people. Age and Ageing 2020;49(6);1093-96
Clinical presentation and outcomes of COVID-19 in older hospitalised patients
We aimed to describe the clinical presentations of COVID-19 in older inpatients with regard to frailty measured by the record-based Multidimensional Prognostic Index (rMPI) tool and to explore possible associations between frailty level and decision of treatment level, change in physical functional abilities and survival. Subsequently, the predictive values of rMPI and Clinical Frailty Scale were compared.
Contact: Lone Winther Lietzen
Publication: Verholt AB, Gregersen M, Gonzalez-Bofill N, Hansen TK, Ebdrup L, Foss CH, Lietzen LW. Clinical presentation and outcomes of COVID-19 in older hospitalised patients assessed by the record-based Multidimensional Prognostic Index, a cross-sectional study. European Geriatric Medicine. 2021 https://doi.org/10.1007/s41999-021-00522-3
Source- and social isolation experienced by older hospitalised patients with COVID-19 and their relatives - a qualitative study
We aim to explore how older patients with COVID-19 and their relatives experience the separation during hospitalization to identify important themes to refine the guidelines concerning isolation.
Contact: Merete Gregersen
Collaborator: Department of Infectious Diseases
Contact: Merete Gregersen
Publication: Gregersen M, Mellemkjær A, Foss A-CH, Blandfort S. Use of single-bed rooms may decrease the incidence of hospital-acquired infections in geriatric patients: A retrospective cohort study in Central Denmark region. Journal of Health Services Research & Policy. 2021 https://doi.org/10.1177/1355819621994866