Søren Baarsgaard Hansen, September 2020

For production of short-lived PET radionuclides, the department operates three medium-sized cyclotrons, two PETtrace systems from GE Healthcare and a Cyclone 18/18 from IBA Radiopharma Solutions. The first PETtrace cyclotron was installed just before the inauguration of the PET-center in Aarhus in 1993, and a second cyclotron, the Cyclone 18/18, was installed in 2009. In 2019 both cyclotrons were moved to the unified Aarhus University Hospital in Skejby and reinstalled after substantial upgraded of various subsystems and targets. In addition, a new PETtrace 880 was installed at the new location.

The PETtrace machines are equipped with six targets, and the acceleration system can deliver beams of protons and deuterons at energies 16,5 and 8,4 MeV respectively. The Cyclone 18/18 cyclotron is equipped with eight targets and is capable of delivering protons at an energy of 18 MeV. The cyclotrons are used routinely for production of the radionuclides 11C, 13N, 15O og 18F, of which several can be delivered as various precursors via online chemical processing modules. All cyclotrons are installed in concrete bunkers including separate maze entrances.